Creatures, bound by the blood of the wolf, that can kill with curses and move at lightening speed, watching the night sky for the rise of the blood-red crescent moon. They are SKINWALKERS. They feed on our flesh and thirst for the taste of human blood. The red moon signals each pack, divided by principles, hell bent to survive an ancient prophecy.

Extreme athlete turned government operative Xander Cage (Vin Diesel) comes out of self-imposed exile, thought to be long dead, and is set on a collision course with deadly alpha warrior Xiang (Donnie Yen) and his team in a race to recover a sinister and seemingly unstoppable weapon known as Pandora’s Box. Recruiting an all-new group of thrill-seeking cohorts, Xander finds himself enmeshed in a deadly conspiracy that points to collusion at the highest levels of world governments.